Pro-insulin → insulinप्राक्-इंसुलिन → इंसुलिन

NCERT Fig 10.3 · Class 12 Biology · Chapter 10 · interactive diagram

Parts and their functions

• Chain B (श्रृंखला B) — One of the two short polypeptide chains of insulin.
• Chain A (श्रृंखला A) — The other short polypeptide chain of insulin.
• C peptide (C पेप्टाइड) — An extra stretch present in pro-insulin. It is NOT present in mature insulin — it is removed during maturation.
• C peptide removed (C पेप्टाइड हटाया गया) — Processing cuts out the C peptide, giving the mature, functional hormone.
• Disulphide bridges (डाइसल्फाइड बंध) — S–S bonds that link chain A and chain B together.

Steps

1. Insulin is made as a pro-hormone, pro-insulin: chains A and B plus an extra C peptide.
2. During maturation the C peptide is removed.
3. Mature insulin = chain A + chain B linked by disulphide bridges.

Original diagram drawn by Simple Learning Hub, based on NCERT Fig 10.3. Report a mistake